College of Psychology: Faculty Articles

Title

Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels

Document Type

Article

Publication Date

1-1-2009

Publication Title

Behav Brain Res

ISSN

0166-4328

Volume

197

Issue/No.

2

Abstract

Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.

DOI

10.1016/j.bbr.2008.08.035

This document is currently not available here.

Peer Reviewed

Find in your library

Share

COinS