Capstone Title

The Florida Manatee, Trichechus manatus latirostris, Papillomavirus: Can it Help Prevent Human Cervical Cancer?

Defense Date

5-2006

Document Type

Capstone

Degree Name

M.S. Marine Biology

First Advisor

Edward Keith

Second Advisor

Andrew Rogerson

Abstract

Using resultsobtained from studying manatee (Trichechus manatus)papilloma viruses, human papilloma viruses and their mechanisms may be better understood. This may expand the range of treatment options available to prevent and remedy human cervical cancer.

Here I examine and compare the manateepapillomavirusand the humanpapillomavirus. Obviously there are numerous similarities which are evident from the research that I’ve conducted. However, the differences may suggest new insights into cancerous processes in humans. If I can elucidate how the manatee immune system functions and predict where and when a latentvirionmight strike, then I can possibly translate that information into human terms, and suggest mechanisms that might allow the human immune system to clear the virus before high-risk forms of the virus have the opportunity to infect. It is desirable to save the manatee from extinction and now saving the manatee may also help save human lives.

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