Biology Faculty Articles

Title

Hypervariable Genomic Variation to Reconstruct the Natural History of Populations: Lessons from the Big Cats

Document Type

Article

Publication Date

1995

Publication Title

Electrophoresis

Keywords

DNA fingerprinting, Cheetah, Coefficient of relatedness curve, Cat microsatellites

ISSN

0173-0835

Volume

16

Issue/No.

1

First Page

1771

Last Page

1774

Abstract

The extent and nature of variation in hypervariable regions of DNA have been used in the past as a means to infer the natural histories of populations. We review the interpretation of the extent of genetic diversity for minisatellite DNA in the cheetah to estimate the timing of a population bottleneck in the species and the potential application of a second class of hypervariable DNA, microsatellite DNA, as a molecular tool to examine the natural histories of felid populations. A calibration curve relating the degree of allele fragment sharing in individuals to relatedness in a captive pedigree of cheetahs is presented. This measurement has important applications for management of potential matings in captive management situations.

Comments

© 1995 VCH Verlagsgesellschaft mbH

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015

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