Title

Patterns of Y and X Chromosome DNA Sequence Divergence During the Felidae Radiation

Authors

Jill Pecon-Slattery, National Cancer Institute at Frederick
Stephen J. O'Brien, National Cancer Institute at FrederickFollow

Document Type

Article

Publication Date

3-1-1998

Publication Title

Genetics

ISSN

0016-6731

Volume

148

Issue/No.

3

First Page

1245

Last Page

1255

Abstract

The 37 species of modern cats have evolved from approximately eight phylogenetic lineages within the past 10 to 15 million years. The Felidae family has been described with multiple measures of morphologic and molecular evolutionary methods that serve as a framework for tracking gene divergence during brief evolutionary periods. In this report, we compare the mode and tempo of evolution of noncoding sequences of a large intron within Zfy (783 bp) and Zfx (854 bp), homologous genes located on the felid Y and X chromosomes, respectively. Zfy sequence variation evolves at about twice the rate of Zfx, and both gene intron sequences track feline hierarchical topologies accurately. As homoplasies are infrequent in patterns of nucleotide substitution, the Y chromosome sequence displays a remarkable degree of phylogenetic consistency among cat species and provides a highly informative glimpse of divergence of sex chromosome sequences in Felidae.

Comments

©1998 by the Genetics Society of America

NSUWorks Citation

Pecon-Slattery, Jill and Stephen J. O'Brien. 1998. "Patterns of Y and X Chromosome DNA Sequence Divergence During the Felidae Radiation." Genetics 148, (3): 1245-1255. https://nsuworks.nova.edu/cnso_bio_facarticles/680

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015