Title

The Promise of Comparative Genomics in Mammals

Authors

Stephen J. O'Brien, National Cancer Institute at FrederickFollow
Marilyn Menotti-Raymond, National Cancer Institute at Frederick
William J. Murphy, National Cancer Institute at Frederick
William Nash, National Cancer Institute at Frederick
Johannes Wienberg, National Cancer Institute at Frederick
Roscoe Stanyon, National Cancer Institute at Frederick
Neal G. Copeland, National Cancer Institute at Frederick
Nancy A. Jenkins, National Cancer Institute at Frederick
James E. Womack, Texas A&M University - College Station
Jennifer A. Marshall Graves, LaTrobe University - Melbourne, Australia

Document Type

Article

Publication Date

10-15-1999

Publication Title

Science

ISSN

0036-8075

Volume

286

Issue/No.

5439

First Page

458

Last Page

462, +479-481

Abstract

Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate-resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.

Comments

©1999 American Association for the Advancement of Science

NSUWorks Citation

O'Brien, Stephen J.; Marilyn Menotti-Raymond; William J. Murphy; William Nash; Johannes Wienberg; Roscoe Stanyon; Neal G. Copeland; Nancy A. Jenkins; James E. Womack; and Jennifer A. Marshall Graves. 1999. "The Promise of Comparative Genomics in Mammals." Science 286, (5439): 458-462, +479-481. https://nsuworks.nova.edu/cnso_bio_facarticles/644

ORCID ID

0000-0001-7353-8301

ResearcherID

N-1726-2015